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Charles W. Mathias, Ph.D.

Dr. Dougherty

Assistant Professor

Department of Psychiatry
The University of Texas Health Science Center at San Antonio

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Biographical Sketch

Dr. Mathias is Assistant Professor in the Division of Alcohol and Drug Abuse within the Department of Psychiatry at the University of Texas Health Science Center at San Antonio (UTHSCSA).  He completed his graduate training in Applied Biopsychology at the University of New Orleans and a National Institute of Mental Health sponsored postdoctoral research fellowship at The University of Texas Health Science Center at Houston.  Dr. Mathias held his first faculty appointment at Wake Forest University Health Sciences in Winston-Salem, NC prior to being recruited to UTHSCSA in 2007.

Dr. Mathias's research interests are focused on understanding the physiological mechanisms that underlie externalizing behaviors exhibited among individuals with psychiatric symptoms and disorders.  As a result, his research approach involves adapting laboratory behavioral procedures used for the assessment of impulsivity to include psychophysiological measurements.  This started at the University of New Orleans, with studies that employed psychophysiological tools (P300, augmenting/reducing, and autonomic reactivity) with traditional neuropsychological tools (e.g. Wisconsin Card Sorting Test).  He has had experience using these techniques in community, forensic, and clinical populations.  Of particular interest has been the study of populations with impulse control difficulties (e.g., patients with traumatic brain injury, antisocial personality disorder, or post-traumatic stress disorder).  This work has included evaluating the effects of medications on psychophysiological processes important to understanding impulsive and aggressive behaviors.  In the last several years, Dr. Mathias has expanded this research to include adolescents, and has begun to use other psychophysiological (e.g., prepulse inhibition and valence modulation) and behavioral (e.g., GoStop Impulsivity Paradigm) procedures.  Within the NRLC, Dr. Mathias's research emphasis is conducting projects that concentrate on developmental psychopathology among adolescents.

Research Interests

  • Psychophysiological Assessment (P300, modification of human startle) 
  • Adolescent Development of Impulse Control
  • Developmental Course of Suicidal Behaviors
  • Childhood Psychopathology, including ADHD and Conduct Disorder
  • Evaluating Pharmacotherapies for the Treatment of Impulse Control
  • Neuropsychological Assessment
  • Characterization of Aggression (impulsive versus premeditated)
  • Development and Evaluation of Longitudinal Retention Strategies

Education

1993 B.S. Behavioral Pharmacology Indiana University
1997 M.S. Applied Biopsychology University of New Orleans
2000 Ph.D. Applied Biopsychology University of New Orleans
2004 Fellowship Psychopharmacology University of Texas HSC Houston

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