Grant Title:

This project compares the direct and interactive contributions of impulsivity, 5-HT, stressful life events, and the outcomes of drug use and suicidality in high-risk adolescents across a 5-year period.

National Institute of Mental Health (R01-MH077684)

Grant Title:

This study will yield data that answers both basic and applied research questions by identifying the underlying mechanism of action of a common medication treatment in a prevalent and difficult-to-treat comorbid condition that starts in childhood and adolescence, and will yield practical information regarding individual treatment differences observed in the clinic.

National Institute of Mental Health (R01-MH081181)

Grant Title:

This study addresses critical gaps in understanding how alcohol and individual differences in underlying biological states affect behavioral processes involved in binge alcohol drinking. This study will yield data to clarify the role of impulsive behavior and serotonin function as mechanisms that contribute to the maintenance of an alcohol binge-drinking episode. With this understanding, we can develop treatments aimed at disrupting such mechanisms using cognitive-behavioral and pharmacological strategies.

National Institute on Alcohol Abuse and Alcoholism (R01-AA018124)

Grant Title:

Alcohol binge drinking produces dangerous levels of intoxication and acute health consequence that confer immediate risks to both the individual and society. This study will provide fundamental information on how specific behavioral processes relate to individual differences in the ability to reduce alcohol consumption. The results of this study will inform the development of treatments aimed at this unique population of problem drinkers, and inform us about how differences in these markers might be used by clinicians to match treatment plans to specific individuals.

National Institute on Alcohol Abuse and Alcoholism (R01-AA014988-07)

Grant Title:

This study will address major gaps in the current knowledge of substance use involvement and impulse control across adolescence. More specifically, we will determine when, how, and to what extent individual differences in impulse control and family histories of substance use disorders contribute to the initiation of substance use, and how subsequent substance use affects developmental trajectories of impulse control.

National Institute on Drug Abuse (R01-DA026868)

Grant Title:

The objectives of this proposed KL-2 career development plan are to complete a balanced set of research, training, and development activities aimed at developing into an independent investigator researching behavioral and corresponding neural mechanisms underlying risks for substance use disorders. Research activities include a project examining neural substrates regulating distinct measures of impulse control in adolescents with Childhood or Adolescents-Onset Conduct Disorder (populations at risk for later substance use disorders), using functional magnetic resonance imaging (fMRI). Training and development activities include seminars and direct mentoring on grant writing, research on drug abuse and other impulsive conditions, responsible conduct of research and further methodological training.

National Center for Research Resources (KL2-RR025766)

Grant Title:

The purpose of this study is to conduct neuroimaging studies in young adults with a family history of alcohol use disorders to examine neurobiological factors associated with increased vulnerability to drug and alcohol abuse.

VA Merit Award