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Immediate and Delayed Memory Tasks

IMT

The Immediate and Delayed Memory Task (IMT/DMT) program is a modified Continuous Performance Test that produces levels of performance that are sensitive to both group differences and pharmacological manipulation, even in high functioning populations.  The IMT/DMT is designed to measure response initiation in impulsive behavior.

Immediate Memory Task

Researchers frequently rely on procedures that are too easy, producing low levels of impulsive errors, which results in a floor effect and reduced sensitivity to group differences.  In the IMT, a series of randomly generated 5-digit numbers (e.g., 38391) appear on a computer monitor for 500 msec at a rate of one per second.  The participant is instructed to respond when two identical numbers are presented in sequence.  The three main types of stimuli are target, filler, and catch stimuli.  A target stimulus if a 5-digit number that is identical to the preceding number.  Responses to target stimuli are recorded as correct detections.  A filler stimulus is a random 5-digit number that appears whenever a target or catch trial is not scheduled to appear.  Responses to filler stimuli are recorded as filler errors. 

And lastly, a catch stimulus is a number that differs from the preceding number by only one digit (position and value determined randomly).  Responses to catch stimuli are recorded as commission errors.  A high number of commission errors indicates an impulsive pattern of responding.

Delayed Memory Task

The Delayed Memory Task functions identical to the Immediate Memory Task except an additional memory component is added. In the DMT, a series of distracter sequences (i.e., 12345) are presented between target stimuli.  Participants are instructed to ignore these distracter sequences but the presentation of these sequences increases the length of time between two target stimuli and evokes a memory component to the task.

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BIBLIOGRAPHY:

A test of alcohol dose effects on multiple behavioral measures of impulsivity.
Dougherty DM, Marsh-Richard DM, Hatzis ES, Nouvion SO, Mathias CW. (2008).
Drug and Alcohol Dependence, 96, 111-120. PubMed

Interactive effects of sex and 5-HTTLPR on mood and impulsivity during tryptophan depletion in health people.
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The effects of alcohol on laboratory-measured impulsivity after L-Tryptophan depletion or loading. 
Dougherty DM, Marsh DM, Mathiaw CW, Dawes MA, Bradley DM, Morgan CJ, Badaway AA (2007). 
Psychopharmacology, 193, 137-150. PubMed

Behavioral impulsivity in adolescents with Conduct Disorder who use marijuana.
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Omega-3 fatty acid supplementation in patients with recurrent self-harm: Single-centre double-blind radomised controlled trial.
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Manic symptoms and impulsivity during bipolar depressive episodes.
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Measuring impulsivity in adolescents with serious substance and conduct problems.
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Assessment, 13, 3-15. PubMed

Reduced anterior corpus callosum white matter integrity is related to increased impulsivity and reduced discriminability in cocaine-dependent subjects: Diffusion tensor imaging. 
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Acute yohimbine increased laboratory-measured impulsivity in normal subjects.
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Biological Psychiatry, 57, 1209-1211. PubMed

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Suicidal behaviors and drug abuse: impulsivity and its assessment. 
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Laboratory measured impulsivity relates to suicide attempt history. 
Dougherty DM, Mathias CW, Marsh DM, Papageorgiou TD, Swann AC Moeller FG  (2004). 
Suicide and Life-Threatening Behavior, 34, 374-385. PubMed

Age at first drink relates to behavioral measures of impulsivity: the immediate and delayed memory tasks.
Dougherty DM, Mathias CW, Tester ML, Marsh DM (2004).   
Alcoholism: Clinical and Experimental Research, 28, 408-414. PubMed

P300 event-related potential amplitude and impulsivityiin cocaine-dependent subjects.
Moeller FG, Barratt ES, Fischer CJ, Dougherty DM, Reilly EL, Mathias CW, Swann AC  (2004).  
Neuropsychobiology, 50, 167-173.  PubMed

Functional MRI study of working memory in MDMA users. 
Moeller FG, Steinberg JL, Dougherty DM, Narayana PA, Kramer LA, Renshaw PF (2004). 
Psychopharmacology, 177, 185-194.  PubMed

Impulsivity: A link between bipolar disorder and substance abuse.
Swann AC, Dougherty DM, Pazzaglia PJ, Pham M, Moeller FG  (2004).
Bipolar Disorders, 6, 204-212.  PubMed

Behavioral impulsivity paradigms: A comparison in hospitalized adolescents with disruptive behavior disorders. 
Dougherty DM, Bjork JM, Harper RA, Marsh DM, Moeller FG, Mathias CW, Swann AC (2003). 
Journal of Child Psychology and Psychiatry, 44, 1145-1157. PubMed

Validation of the Immediate and Delayed Memory Tasks in hospitalized adolescents with disruptive behavior disorders. 
Dougherty DM, Bjork JM, Harper RA, Mathias CW, Moeller FG, Marsh DM (2003). 
Psychological Record, 53, 509-532. 


Familial transmission of Continuous Performance Test behavior: Attentional and impulsive response characteristics.
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Journal of General Psychology, 130, 5-21.  PubMed

Immediate and delayed memory tasks: a computerized behavioral measure of memory, attention, and impulsivity.
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Comparison of women with high and low trait impulsivity using behavioral models of response-disinhibition and reward-choice.
Marsh DM, Dougherty DM, Mathias CW, Moeller FG, Hicks LR  (2002).
Personality and Individual Differences, 33, 1291-1310.

Reliability estimates for the Immediate and Delayed Memory Tasks.
Mathias CW, Marsh DM, Dougherty DM  (2002).   
Perceptual and Motor Skills,95, 559-569.  PubMed

Two models of impulsivity: Relationship to personality traits and psychopathology. 
Swann AC, Bjork JM, Moeller FG, Dougherty DM (2002). 
Biological Psychiatry, 15, 988-994.  PubMed

Effects of moderate and high doses of alcohol on attention, impulsivity, discriminability, and response bias in immediate and delayed memory task performance.
Dougherty DM, Marsh DM, Moeller FG, Chokshi RV, Rosen VC (2000). 
Alcoholism: Clinical and Experimental Research, 24, 1702-1711.  PubMed

Alcohol increases commission errors for a continuous performance test.
Dougherty DM, Moeller FG, Steinberg JL, Marsh DM, Hines SE, Bjork JM (1999).
Alcoholism: Clinical and Experimental Research, 23, 1342-1351.  PubMed

Immediate versus delayed visual memory task performance among schizophrenic patients and normal control subjects.
Dougherty DM, Steinberg JL, Wassef AA, Medearis D, Cherek DR, Moeller FG (1998).
Psychiatry Research, 79, 255-265.  PubMed

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